 |
Razvan Ioan Ionasec razvan(at)ionasec.com |
|
Razvan is a Project Manager with Siemens Corporate Research, Princeton NJ, USA, leading teams of scientists and engineers in the U.S., Germany and Romania. He focuses on the development of innovative medical imaging technologies for advanced cardiovascular disease treatment. In 2010, he received his Ph.D. degree from the Department of Computer Aided Medical Procedures at Technical University Munich and in 2007 his Dipl. Inf. Univ. (M.Sc.) in Computer Science from the Friedrich Alexander University, Erlangen-Nuremberg in Germany. Razvan has co-authored 30+ papers and patent applications, received the Young Scientist Award at MICCAI 2010, and serves as technical lead for the Sim-e-Child project funded by the European Commission. He is passionate about High-tech Entrepreneurship and the Cardiovascular Business, and enjoys traveling, playing volleyball and tennis. |
|
 |
|
|
|
|
Sim-e-Child |
| Sim-e-Child is a FP7 European Commision funded STREP project that aims to
develop a grid-enabled platform for large scale simulations in
paediatric cardiology, providing a collaborative environment for
constructing and validating multi-scale and personalized models of a
growing heart and vessels. The objective of the Sim-e-Child is to
strengthen the impact of the Health-e-Child project by creating an
international simulation and validation environment for paediatric
cardiology, supported by integrated data repositories. The project will
advance the state-of-the-art by providing comprehensive and patient
specific models for the dynamic and longitudinal interactions occurring
in the left heart, with a focus on the congenital aortic arch disease
and repair. |
|
|
FullValve |
| The central problem addressed by the FullValve project is the lack of appropriate technology to exploit the potential of non-invasive investigation methods in cardiology. One of the main challenges in cardiology comes from the complex physiology of the heart its dynamics, and complicated interconnection of the anatomical structures. From a technical perspective, the mathematical formulation of an efficient valves representation was until recently and unsolved problem. Yet another provocation comes from the difficulty of design algorithms which can process huge amount of data produces by nowadays’ medical scanners. It is generally agreed that automatic generate clinical information as well as any kind of decision support system are extremely hard to get validated and accepted in the clinical practice due to the intrinsic limitations of dealing with humans and their health. FullValve provides automatic clinical evaluation, personalized surgical planning and predictive decision support for valve diseases patients. That is achieved by combing the advantages of newest medical scanners with robust statistical algorithms | |
|
Castomat |
| Castomat is a Siemens product for optimizing the lifecycle-costs of industrial plants. It performs condition base maintenance through sophisticated algorithms that analyze, diagnose and identify trends of critical machine parts. The main benefits of intelligent condition monitoring are: down-time reduction, maintenance cost reduction, plant performance optimization and operating costs savings. As part of the software development team, I was responsible for designing and implementing modules for signal monitoring and storage. I was also involved in customer support and quality assurance activities. | |
|
Food.ro |
| Started as a high-school project and developed together with a colleague, in 2001 this e-shop has become the first virtual restaurant in Romania.
The e-shop has revolutionary features such as custom hamburger creation and automated order billing in the back-office.
As the inventors and leaders of this project, we first created a business plan and a prototype for our virtual restaurant.
Then we implemented all related software and marketed the site as a service. After on-site customer implementation (front-office and back-office) we implemented an advertising campaign together with our partner, the Millenium Restaurant.
‘Food.ro – The Virtual Restaurant” – was well known at the time, continuously highlighted in the media (TV, newspapers, etc.) as a great innovation, and rewarded with several awards in regional and national contests.
|
|
|
Wapme |
| Wapme Systems is a provider of high-profile Web and Wap solutions. As a software developer, I had the opportunity to participate in exciting projects such as the implementation of the multimedia messaging service, based on Kannel Wap and SMS Gateway, for on of the first MMS-capable terminals on the market – Nokia 7650 and Ericsson T68, and the automated generated marketing content for Pfizer products. | |
| 2011/12 |
Leipzig-Dallas International Heart: A Glimpse Into The Future – Dyna-CT, Heart Valve Models And Other Toys, Leipzig, Germany - http://www.ltcs-leipzig.com |
| 2011/09 |
MICCAI 2011 Tutorial for Image-guided Interventions Technology and Applications: Catheter Based Interventions, Toronto, Canada - http://campar.in.tum.de/IGI/WebHome |
| 2011/05 |
Workshop on Advanced Imaging and Visualization: Engineering the Heart, Kloster Plankstetten, Germany - http://campar.in.tum.de/ImVis/WebHome |
| 2010/09 |
MICCAI 2010 Workshop on Statistical Atlases and Computational Models of the Heart: Patient-specific Modeling of the Heart Valves: Applications to Cardiovascular Disease Management, Beijing, China - http://cilab2.upf.edu/stacom_cesc10/index.php |
2011 |
|
 |
R. Ionasec, D. Vitanovski, D. Comaniciu : Morphological and Functional Modeling of the Heart Valves and Chambers, Patient-Specific Modeling in Tomorrow's Medicine, Springer Jan 2012, ISBN 978-3-642-24617-3. |
|
T. Mansi, I. Voigt, E. Assoumou Menge, R. Ionasec, B. Georgescu, T. Noack, J. Seeburger, D. Comaniciu: Towards Patient-Specific Finite-Element Simulation of Mitral Clip Procedure, MICCAI 2011, Toronto, Canada, September 18-22 2011. |
|
I. Voigt, T. Mansi, R. Ionasec, E. Mengue, H. Houle, B. Georgescu, J. Hornegger, D. Comaniciu: Robust Physically-Constrained Modeling of the Mitral Valve and Subvalvular Apparatus, MICCAI 2011, Toronto, Canada, September 18-22 2011. |
|
S. Grbic, R. Ionasec, Y. Wang, T. Mansi, B. Georgescu, M. John, J. Boese, Y. Zheng, N. Navab, D. Comaniciu: Model-Based Fusion of Multi-Modal Volumetric Images: Application to Transcatheter Valve Procedures, MICCAI 2011, Toronto, Canada, September 18-22 2011. |
|
K. Ralovich, R. Ionasec, V. Mihalef, , B. Georgescu, A. Everett, N. Navab, D. Comaniciu : Computational Fluid Dynamics Framework for Large-Scale Simulation in Pediatric Cardiology , MICCAI 2011 Workshop for Computational Biomechanics for Medicine VI , Toronto, Canada, September 18-22 2011. |
|
D. Vitanovski, A. Tsymbal, R. Ionasec, A. Greiser, E. Mueller, X. Lu, J. Hornegger, D. Comaniciu : Accurate Regression-based 4D Mitral Valve Segmentation from 2D MRI Slices , MICCAI 2011 Workshop for Machine Learning in Medical Imaging, Toronto, Canada, September 18-22 2011. |
|
D. Vitanovski, A. Tsymbal, R. Ionasec, B. Georgescu, S. K. Zhou, J. Hornegger, D. Comaniciu: Learning distance function for regression-based 4D pulmonary trunk model reconstruction estimated from sparse MRI data, SPIE 2011, Volume: 7964. |
|
V. Mihalef, R. Ionasec, G. Georgescu, I. Voigt, M. Suehling, D. Comaniciu: Patient-specific modelling of whole heart anatomy, dynamics and haemodynamics from four-dimensional cardiac CT images, Royal Society Interface Focus Journal, June 6, 2011 1:286-296. |
|
I. Voigt, T. Mansi, V. Mihalef, R. Ionasec, A. Calleja, E. Mengue, P. Sharma, H. Houle, B. Georgescu, J. Hornegger, D. Comaniciu: Patient-Specific Model of Left Heart Anatomy, Dynamics and Hemodynamics from 4D TEE: A First Validation Study, Sixth International Conference on Functional Imaging and Modeling of the Heart, FIMH 2011, May 25-27, 2011. |
|
R. Ionasec, Michael Suehling, Dorin Comaniciu: Sim-e-Child: Grid-Enabled Platform for Simulations in Paediatric Cardiology –Toward the Personalized Virtual Child Heart, VPH Network of Excellence Newsletter, Number 5, 2011 |
|
A. Calleja, R. Ionasec, P. Thavendiranathan, S. Liu, H. Houle, C. Sai-Sudhakar, J. Crestanello, W. Perez, M. Andritsos, T. Ryan, M. Vannan: Automated Quantification of Aortic Root Remodeling in Aortic Stenosis Using Volumetric 3-D Transesophageal Echocardiography: Implications for Trans-Catheter Aortic Valve Replacement (TAVR), American College of Cardiology Annual Meeting - ACC 2011, New Orleans, USA, April 2011. |
|
K. Stiver, A. Calleja, R. Ionasec, I. Voigt, P. Thavendiranathan, S. Liu, H. Houle, N. De Michelis, T. Ryan, M. Vannan: Superior Reproducibility of Automated 3-D Surgical Anatomy of Normal and Abnormal Mitral Valve when Compared to a Manual Approach, American Society of Echocardiography Annual Meeting - ASE 2011, Montreal, Canada, June 2011. |
|
A. Calleja, K. Stiver, P. Thavendiranathan, S. Liu, R. Ionasec, I. Voigt, H. Houle, N. De Michelis, T. Ryan, M. Vannan: Automated Quantitative 3-D Echocardiography of The Surgical Mitral Valve Anatomy in Functional Mitral Regurgitation to Guide Mitral Valve Repair, American Society of Echocardiography Annual Meeting - ASE 2011, Montreal, Canada, June 2011. |
|
P.J. Spevak, R.I. Ionasec, D. Comaniciu, K.W. Holmes, G. Pongiglione, A.D. Everett: Development and validation of a novel automated learning based algorithm for quantification of MRI right ventricular volume in Tetralogy of Fallot, Association of European Paediatric Cardiology Annual Meeting - AEPC 2011, Granada, Spain, May 2011. |
2010 |
|
|
R. Ionasec: Patient-specific Modeling and Quantification of the Heart Valves from Multimodal Cardiac Images, PhD Dissertation 2010. |
|
R. Ionasec, I. Voigt, B. Georgescu, Y. Wang, H. Houle, F. Vega-Higuera, N. Navab, D. Comaniciu: Patient-Specific Modeling and Quantification of the Aortic and Mitral Valves From 4-D Cardiac CT and TEE, IEEE TMI 2010, Vol. 29, No. 9, pp. 1636-1651. |
|
S. Grbic, R. Ionasec, D. Vitanovski, I. Voigt, B. Georgescu, , N. Navab, D. Comaniciu: Complete Valvular Heart Apparatus Model from 4D Cardiac CT, Medical Image Computing and Computer Assisted Intervention - MICCAI 2010,Beijing, China, September 20-24 2010. |
|
D. Vitanovski, R. Ionasec, A. Tsymbal, B. Georgescu, M. Huber, J. Hornegger, D. Comaniciu: Cross-modality Assessment and Planning for Pulmonary Trunk Treatment using CT and MRI imaging, Medical Image Computing and Computer Assisted Intervention - MICCAI 2010, Beijing, China, September 20-24 2010. |
|
I. Voigt, R. Ionasec, B. Georgescu, J. Bose, J. Hornegger, D. Comaniciu: Computational Decision Support and Intraoperative Guidance for Percutaneous Aortic Valve Implantation, Medical Image Computing and Computer Assisted Intervention Workshop - MIAR 2010, Beijing, China, September 20-24 2010. |
|
V. Mihalef, R. Ionasec, Y. Wang, Y. Zheng, B. Georgescu, D. Comaniciu: Patient-specific Modeling of Left Heart Anatomy, Dynamics and Hemodynamics from High Resolution 4D CT, IEEE International Symposium on Biomedical Imaging - ISBI 2010, Rotterdam, Netherlands, April 2010. |
|
A. Calleja, R. Ionasec, H. Houle, S. Liu, J. Dickerson, P. Thavendiranathan, C. Sai-Sudhakar, J. Crestanello, T. Ryan, M. Vannan: Automated Quantitative Modeling of the Aortic Valve and Root in Aortic Regurgitation Using Volume 3-D Transesophageal Echocardiography, American College of Cardiology Annual Meeting - ACC 2010, Atlanta, USA, March 2010. |
|
V. Mihalef, R. Ionasec, P. Sharma, B. Georgescu, M. Huber, D. Comaniciu: Patient-Specific Modeling of Whole Heart Anatomy, Dynamics and Hemodynamics from 4D cardiac CT Images, VPH Virtual Physiological Human - Annual Conference 2010, Brussels, Belgium, October 2010. |
|
R. Ionasec, V. Mihalef, B. Georgescu, N. Navab, D. Comaniciu: Patient-Specific Modelling of Left-Heart Anatomy, Dynamics and Hemodynamics from 4D cardiac CT Images, BMT Biomedizinische Technik 2010, Rostock, Germany, October 2010. |
|
I. Voigt, D. Vitanovski, R. Ionasec, A. Tsymbal, B. Georgescu, K. Zhou, M. Huber, N. Navab, J. Hornegger, D. Comaniciu: Learning discriminative distance functions for valve retrieval and improved decision support in valvular heart disease, SPIE Medical Imaging, 2010, San Diego, USA, February 2010. |
|
S. Grbic, R. Ionasec, Y. Zheng, D. Zaeuner, B. Georgescu, D. Comaniciu: Aortic Valve and Ascending Aortic Root Modeling from 3D and 3D+t CT, SPIE Medical Imaging, 2010, San Diego, USA, February 2010. |
|
R. Ionasec: 4-D modeling increases accuracy in valve disease diagnosis, Siemens Healthcare Ultrasound Corporate News 2010. |
|
R. Ionasec, I. Voigt, V. Mihalef, S. Grbic, D. Vitanovski, Y. Wang, Y. Zheng, J. Hornegger, N. Navab, B. Georgescu, D. Comaniciu: Patient-specific Modeling of the Heart: Applications to Cardiovascular Disease Management In: Camara, Oscar; Sermesant, Maxime; Rhode, Kawal; Pop, Mihaela; Smith, Nic; Young, Alistair (Eds.) Proceedings of the International Workshop on Statistical Atlases and Computational Models of the Heart: Mapping Structure and Function (STACOM Beijing 20.09.2010) Heidelberg : Springer 2010 |
2009 |
|
|
R. Ionasec, Y. Wang, B. Georgescu, I. Voigt, N. Navab, D. Comaniciu: Robust Motion Estimation Using Trajectory Spectrum Learning: Application to Aortic and Mitral Valve Modeling from 4D TEEInternational Conference on Computer Vision (ICCV), Kyoto, Japan, 2009. |
|
R. Ionasec, B. Heigl, J. Hornegger: Acquisition-related motion compensation for digital subtraction angiography, Computerized Medical Imaging and Graphics, Volume 33, Issue 4, Pages 247-332 (June 2009). |
|
A. Barbu, R. Ionasec: Boosting Cross-Modality Image Registration, Joint Urban Remote Sensing, Shanghai 2009. |
|
I. Voigt, R. Ionasec, B. Georgescu, H. Houle, M. Huber, J. Hornegger, D. Comaniciu: Model-driven physiological assessment of the mitral valve from 4D TEE , SPIE Medical Imaging, 2009, Orlando, USA, February 2009. |
|
R. Ionasec, A. Tsymbal, D. Vitanovski, B. Georgescu, K. Zhou, N. Navab, D. Comaniciu: Shape-based diagnosis of the aortic valve , SPIE Medical Imaging, 2009, Orlando, USA, February 2009. |
|
D. Vitanovski, R. Ionasec, B. Georgescu, M. Huber, R. Taylor, J. Hornegger, D. Comaniciu: Personalized pulmonary trunk modeling for intervention planning and valve assessment estimated from CT data, Medical Image Computing and Computer Assisted Intervention (MICCAI), London, UK, September 20-24 2009. |
|
R. Ionasec, I. Voigt, B. Georgescu, H. Houle, J. Hornegger, N. Navab, D. Comaniciu: Modeling and assessment of the Aortic-Mitral valve coupling from 4D TEE and CT , Medical Image Computing and Computer Assisted Intervention (MICCAI), London, UK, September 20-24 2009. |
2008 |
|
|
E. Gassner, R. Ionasec, B. Georgescu, S. Vogt, U. J. Schoepf, D. Comaniciu: Performance of a Dynamic Aortic Valve Model for Quantification of the Opening Area at Cardiac MDCT . Comparison to Manual Planimetry, Radiological Society of North America, RSNA, 2008, Chicago, USA, November 2008. |
|
R. Ionasec, B. Georgescu, D. Comaniciu, S. Vogt, U. J. Schoepf, E. Gassner: Patient Specific 4D Aortic Root Models Derived from Volumetric Image Data Sets , Radiological Society of North America, RSNA, 2008, Chicago, USA, November 2008. |
|
R. Ionasec, B. Georgescu, E. Gassner, S. Vogt, O. Kutter, M. Scheuering, N. Navab, D. Comaniciu: Dynamic model-driven quantification and visual evaluation of the aortic valve from 4D CT , Medical Image Computing and Computer-Assisted Intervention, MICCAI, 2008, New York, USA, September 6-10 2008. |
|
J. Choi, B. Georgescu, R. Ionasec, S. Raman, G. Hong, S. Liu, H. Houle, M. A. Vannan: Novel Semi-Automatic Quantitative Assessment of The Aortic Valve and Aortic Root from Volumetric 3D Echocardiography: Comparison to Volumetric Cardiac Computed Tomography (CT) , AHA, New Orleans, USA, November 2008. |
|
United States Patent Application 20090154785: Method and system for dynamic pulmonary trunk modeling in computed tomography and magnetic resonance imaging. |
|
United States Patent Application 20090123050: Method and system for automatic quantification of aortic valve function from 4D computed tomography data using a physiological model. |
|
United States Patent Application 20100240996: VALVE ASSESSMENT FROM MEDICAL DIAGNOSTIC IMAGING DATA. |
|
United States Patent Application 20100239147: Method and System for Dynamic Pulmonary Trunk Modeling and Intervention Planning. |
|
United States Patent Application 20100067768: Method and System for Physiological Image Registration and Fusion. |
|
United States Patent Application 20100070249: Method and System for Generating a Personalized Anatomical Heart Model |
|
United States Patent Application 20100280352: Method and System for Multi-Component Heart and Aorta Modeling for Decision Support in Cardiac Disease. |